Think you know Baltimore from its setting in popular films and TV shows? Think again. This city on the Chesapeake Bay has been a major seaport since the 1700s and boasts historical sites like Fort McHenry and the Baltimore Maritime Museum. Its modern charms include Camden Yards, the National Aquarium, and a skyline and Inner Harbor district that continue to evolve with new developments. Get a 360-degree view of it all from the top of the Baltimore World Trade Center, or book a sailboat excursion on the bay. Just don’t leave without feasting on Maryland’s famous crabs and other savory seafood.